Independent and combined effects of obesity and traumatic joint injury to the structure and composition of rat knee cartilage. Connective Tissue Res. 2024 Mar 26. Karjalainen K, Tanska P, Collins KH, Herzog W, Korhonen RK, Moo EK. PMID: 38530304.
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Evolution and Advancements in Genomics and Epigenomics in OA Research: How Far We Have Come. Osteoarthritis and Cartilage. 2024 Feb 28. Ramos Y, Rice SJ, Ali SA, Pastrello C, Jurisica I, Rai MF, Collins KH, Lang A, Maerz T, Geurts J, Ruiz-Romero C, June RK, Appleton CT, Rockel JS, Kapoor M. PMID: 38428513.
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Chondrocyte-Specific Knockout of PIEZO Ion Channels Protects Against Post-Traumatic Osteoarthritis. Orthopaedic Proceedings. 2024 Jan 02. Ely EV, Collins KH, Lenz K, Paradi S, Liedtke W, Chen Y, Guilak F.

Designer Fat Cells: Adipogenic Differentiation of CRISPR-Cas9 Genome-Engineered Induced Pluripotent Stem Cells. European Cells and Materials.  2024 Jan 02. Ely EV, Kapinski AT, Paradi SG, Tang R, Guilak F, Collins KH. PMID: 37961399.
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Three Decades of Advancements in Osteoarthritis Research: Insights from Transcriptomic, Proteomic, and Metabolomic Studies. Osteoarthritis Cartilage. 2023 Dec 02. Rai MF, Collins KH, Lang A, Maerz T, Geurts J, Ruiz-Romero C, June RK, Ramos Y, Rice SJ, Ali SA, Pastrello C, Jurisica I, Thomas Appleton C, Rockel JS, Kapoor M. PMID: 38049029.
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Aerobic and Resistance Training Attenuate Differently Knee Joint Damage Caused by a High-Fat-High-Sucrose Diet in a Rat Model. Cartilage. 2023 Sep 01; 19476035231193090. Abughazaleh N, Boldt K, Rios JL, Mattiello SM, Collins KH, Seerattan RA, Herzog W. PMID: 37655800.
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Post or Perish? Social Media Strategies for Disseminating Orthopedic Research. J Orthop Res. 2023 May 10. Buettmann EG, Chlebek C, Lockard CA, Clayton SW, Lewis KJ, Collins KH. PMID: 37163368.
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Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine Therapy. Gels. 2023 Feb 20; 9(2). Collins KH, Pferdehirt L, Saleh LS, Savadipour A, Springer LE, Lenz KL, Thompson DM, Oswald SJ, Pham CTN, Guilak F. PMID: 36826339; PMCID: PMC9956980

The role of PIEZO ion channels in the musculoskeletal system. Am J Physiol Cell Physiol. 2023 03 01; 324(3):C728-C740. Savadipour A, Palmer D, Ely EV, Collins KH, Garcia-Castorena JM, Harissa Z, Kim YS, Oestrich A, Qu F, Rashidi N, Guilak F. PMID: 36717101; PMCID: PMC10027092.

#OrthoTwitter: Relationship Between Author Twitter Utilization and Academic Impact in Orthopaedic Surgery. Cureus. 2023 Jan; 15(1):e33978. Halvorson RT, Allahabadi S, Cevallos N, Foley AJ, Collins K, Torres Espin A, Feeley BT, Pandya NK, Bailey JF. PMID: 36814734; PMCID: PMC9939849.

Trimming the fat - is leptin crosstalk the link between obesity and osteoarthritis? Osteoarthritis Cartilage. 2023 01; 31(1):23-25. Collins KH, Guilak F. PMID: 36273787.
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Leptin mediates the regulation of muscle mass and strength by adipose tissue. J Physiol. 2022 08; 600(16):3795-3817. Collins KH, Gui C, Ely EV, Lenz KL, Harris CA, Guilak F, Meyer GA. PMID: 35844058; PMCID: PMC9378542


A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery. Sci Adv. 2021 Sep 03; 7(36):eabj1414. Choi YR, Collins KH, Springer LE, Pferdehirt L, Ross AK, Wu CL, Moutos FT, Harasymowicz NS, Brunger JM, Pham CTN, Guilak F. PMID: 34516920; PMCID: PMC8442875

Taxonomic changes in the gut microbiota are associated with cartilage damage independent of adiposity, high fat diet, and joint injury. Sci Rep. 2021 07 15; 11(1):14560. Collins KH, Schwartz DJ, Lenz KL, Harris CA, Guilak F. PMID: 34267289; PMCID: PMC8282619

Contractility of permeabilized rat vastus intermedius muscle fibres following high-fat, high-sucrose diet consumption. Appl Physiol Nutr Metab. 2021 Nov; 46(11):1389-1399. Smith IC, Ostertag C, O'Reilly JJ, Rios JL, Klancic T, MacDonald GZ, Collins KH, Reimer RA, Herzog W. PMID: 34139131. 

Immunoengineering the next generation of arthritis therapies. Acta Biomater. 2021 10 01; 133:74-86. Klimak M, Nims RJ, Pferdehirt L, Collins KH, Harasymowicz NS, Oswald SJ, Setton LA, Guilak F. PMID: 33823324; PMCID: PMC8941669

Adipose tissue is a critical regulator of osteoarthritis. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). Collins KH, Lenz KL, Pollitt EN, Ferguson D, Hutson I, Springer LE, Oestreich AK, Tang R, Choi YR, Meyer GA, Teitelbaum SL, Pham CTN, Harris CA, Guilak F. PMID: 33443201; PMCID: PMC7817130


Is Obesity a Disease of Stem Cells? Cell Stem Cell. 2020 07 02; 27(1):15-18. Oestreich AK, Collins KH, Harasymowicz NS, Wu CL, Guilak F. PMID: 32619511; PMCID: PMC8715393

Infiltration of intramuscular adipose tissue impairs skeletal muscle contraction. J Physiol. 2020 07; 598(13):2669-2683. Biltz NK, Collins KH, Shen KC, Schwartz K, Harris CA, Meyer GA. PMID: 32358797; PMCID: PMC8767374

Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet-induced obesity. Sci Adv. 2020 05; 6(19):eaaz7492. Tang R, Harasymowicz NS, Wu CL, Collins KH, Choi YR, Oswald SJ, Guilak F. PMID: 32426485; PMCID: PMC7209997

The role of macrophages in osteoarthritis and cartilage repair. Osteoarthritis Cartilage. 2020 05; 28(5):544-554. Wu CL, Harasymowicz NS, Klimak MA, Collins KH, Guilak F. PMID: 31926267; PMCID: PMC7214213

Impact of age on host responses to diet-induced obesity: Development of joint damage and metabolic set points. J Sport Health Sci. 2020 03; 9(2):132-139. Collins KH, MacDonald GZ, Hart DA, Seerattan RA, Rios JL, Reimer RA, Herzog W. PMID: 32099721; PMCID: PMC7031772


Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies. J Orthop Res. 2019 06; 37(6):1287-1293. Guilak F, Pferdehirt L, Ross AK, Choi YR, Collins K, Nims RJ, Katz DB, Klimak M, Tabbaa S, Pham CTN. PMID: 30977548; PMCID: PMC6546536

Protective effect of prebiotic and exercise intervention on knee health in a rat model of diet-induced obesity. Sci Rep. 2019 03 07; 9(1):3893. Rios JL, Bomhof MR, Reimer RA, Hart DA, Collins KH, Herzog W. PMID: 30846801; PMCID: PMC6405910

Nanotherapy Targeting NF-κB Attenuates Acute Pain After Joint Injury. Precis Nanomed. 2019; 2(1):245-248. Yan H, Duan X, Collins KH, Springer LE, Guilak F, Wickline SA, Rai MF, Pan H, Pham CTN. PMID: 31681908; PMCID: PMC6824724

Maternal prebiotic supplementation reduces fatty liver development in offspring through altered microbial and metabolomic profiles in rats. FASEB J. 2019 04; 33(4):5153-5167. Paul HA, Collins KH, Nicolucci AC, Urbanski SJ, Hart DA, Vogel HJ, Reimer RA. PMID: 30629464.
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Genome Engineering for Osteoarthritis: From Designer Cells to Disease-Modifying Drugs. Tissue Eng Regen Med. 2019 08; 16(4):335-343. Choi YR, Collins KH, Lee JW, Kang HJ, Guilak F. PMID: 31413938; PMCID: PMC6675820


Association of Metabolic Markers with self-reported osteoarthritis among middle-aged BMI-defined non-obese individuals: a cross-sectional study. BMC Obes. 2018; 5:23. Collins KH, Sharif B, Reimer RA, Sanmartin C, Herzog W, Chin R, Marshall DA. PMID: 30186613; PMCID: PMC6120068

High-fat/high-sucrose diet-induced obesity results in joint-specific development of osteoarthritis-like degeneration in a rat model. Bone Joint Res. 2018 Apr; 7(4):274-281. Collins KH, Hart DA, Seerattan RA, Reimer RA, Herzog W. PMID: 29922445; PMCID: PMC5987701

Obesity, Metabolic Syndrome, and Musculoskeletal Disease: Common Inflammatory Pathways Suggest a Central Role for Loss of Muscle Integrity. Front Physiol. 2018; 9:112. Collins KH, Herzog W, MacDonald GZ, Reimer RA, Rios JL, Smith IC, Zernicke RF, Hart DA. PMID: 29527173; PMCID: PMC5829464

Potential Impact of Metabolic and Gut Microbial Response to Pregnancy and Lactation in Lean and Diet-Induced Obese Rats on Offspring Obesity Risk. Mol Nutr Food Res. 2018 02; 62(4). Paul HA, Collins KH, Bomhof MR, Vogel HJ, Reimer RA. PMID: 29193674. 

Diet-induced obesity leads to pro-inflammatory alterations to the vitreous humour of the eye in a rat model. Inflamm Res. 2018 Feb; 67(2):139-146. Collins KH, Herzog W, Reimer RA, Reno CR, Heard BJ, Hart DA. PMID: 29075814.
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Acute and chronic changes in rat soleus muscle after high-fat high-sucrose diet. Physiol Rep. 2017 May; 5(10):e13270. Collins KH, Hart DA, Smith IC, Issler AM, Reimer RA, Seerattan RA, Rios JL, Herzog W. PMID: 28533262; PMCID: PMC5449557

Association of body mass index (BMI) and percent body fat among BMI-defined non-obese middle-aged individuals: Insights from a population-based Canadian sample. Can J Public Health. 2017 03 01; 107(6):e520-e525. Collins KH, Sharif B, Sanmartin C, Reimer RA, Herzog W, Chin R, Marshall DA. PMID: 28252369; PMCID: PMC6972441


A High-Fat High-Sucrose Diet Rapidly Alters Muscle Integrity, Inflammation and Gut Microbiota in Male Rats. Sci Rep. 2016 11 17; 6:37278. Collins KH, Paul HA, Hart DA, Reimer RA, Smith IC, Rios JL, Seerattan RA, Herzog W. PMID: 27853291; PMCID: PMC5112513

Reduced knee adduction moments for management of knee osteoarthritis:: A three month phase I/II randomized controlled trial. Gait Posture. 2016 10; 50:60-68. Lewinson RT, Vallerand IA, Collins KH, Wiley JP, Lun VMY, Patel C, Woodhouse LJ, Reimer RA, Worobets JT, Herzog W, Stefanyshyn DJ. PMID: 27580080.
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High-fat high-sucrose diet leads to dynamic structural and inflammatory alterations in the rat vastus lateralis muscle. J Orthop Res. 2016 12; 34(12):2069-2078. Collins KH, Hart DA, Reimer RA, Seerattan RA, Waters-Banker C, Sibole SC, Herzog W. PMID: 26990324.
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Response to diet-induced obesity produces time-dependent induction and progression of metabolic osteoarthritis in rat knees. J Orthop Res. 2016 06; 34(6):1010-8. Collins KH, Hart DA, Reimer RA, Seerattan RA, Herzog W. PMID: 26572064.
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Relationship between inflammation, the gut microbiota, and metabolic osteoarthritis development: studies in a rat model. Osteoarthritis Cartilage. 2015 Nov; 23(11):1989-98. Collins KH, Paul HA, Reimer RA, Seerattan RA, Hart DA, Herzog W. PMID: 26521745. 
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Using diet-induced obesity to understand a metabolic subtype of osteoarthritis in rats. Osteoarthritis Cartilage. 2015 Jun; 23(6):957-65. Collins KH, Reimer RA, Seerattan RA, Leonard TR, Herzog W. PMID: 25659656.
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Reduced knee joint loading with lateral and medial wedge insoles for management of knee osteoarthritis: a protocol for a randomized controlled trial. BMC Musculoskelet Disord. 2014 Dec 03; 15:405. Lewinson RT, Collins KH, Vallerand IA, Wiley JP, Woodhouse LJ, Reimer RA, Worobets JT, Herzog W, Stefanyshyn DJ. PMID: 25467955; PMCID: PMC4265477

Ground reaction force estimates from ActiGraph GT3X+ hip accelerations. PLoS One. 2014; 9(6):e99023. Neugebauer JM, Collins KH, Hawkins DA. PMID: 24914946; PMCID: PMC4051663.